Determine the molecular abnormalities and prognosis

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1: What process does the body employ to get rid of the continuously dying cells while cells grow and regenerate? What kind of cells, after all, can't be replenished once they've died?

2: I'm not sure why some autosomal dominant disorders have a male or female preponderance, for example, I've never seen a woman with Marfan's syndrome. I was blaming it on imprinting, but after reading more about it, I realized it wasn't the case.

3: We've heard that some colon cancer tumors are linked to microsatellite instability. What exactly does this imply?

4: I've heard that microarrays are utilized to determine the molecular abnormalities and prognosis in some leukemia patients. What are microarrays, and how do they work?

5: What causes myopathy in mitochondrial diseases?

6: Why do patients with certain hereditary illnesses present earlier and with progressively worse symptoms in consecutive generations?

7: Does a normal serum uric acid level rule out Lesch-Nyhan syndrome diagnosis?

8: How is retinoblastoma an autosomal dominant illness if both RB genes must be mutated for the disease to manifest?

Reference no: EM132929942

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