Determine systemic clearance, renal clearance

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Reference no: EM133706027

Procainamide is used for the treatment of ventric- ular tachyarrhythmia. Its therapeutic range is 4- 8 µg mL and it is administered intravenously as well as by extravascular routes. The elimination half life and the apparent volume of distribution of procainamide are reported to be 3 h and 2L kg¹, respectively. Determine systemic clearance, renal clearance and metabolic clearance for the drug from the available information.

Reference no: EM133706027

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