Reference no: EM132935487
1) Evaluate the following statement. An answer of True or False is worth zero points. Justify your answer using an explanation. Base pair substitutions that don't alter amino acids in polypeptides create new alleles.
2) Recombination via crossing over is being studied in a diploid species among four genes (A through D) known to be on the same chromosome. Prior study demonstrates that the genes are arranged as follows and only two chromosomal genotypes are initially present. The two chromosomes genotypes are
A--------- B----------c-----------D
a----------b----------C-----------D
a) Determine all possible chromosomal genotypes with respect to these four genes that possibly can be created by crossing over in a population. Show your work via a series of diagrams of crossing over.
b) What is the maximum number of chromosomal haplotypes (for this example) produced by a single cell that enters meiosis? SHOW YOUR WORK
c) Can a single individual in the population produce more haplotypes during meiosis than produced by the single cell followed above? EXPLAIN.
3) Shown below is a diagrammatic representation of a pericentric inversion for a diploid species. The centromere indicated by the asterisk occurs between D and E. Use your knowledge of pericentric inversions to determine which chromosomal haplotypes are most commonly found within populations of gametes produce by an individual who is an inversion heterozygote, following a crossover between the homologs within the inverted sequence?
b) EXPLAIN WHY
A-------B------C------D----*----E----------F
A-------E---*---D------C--------B----------F
4) Evaluate the following statement. An answer of True or False is worth zero points. Justify your answer using an explanation. The rate of base pair substitutions (mutations) in exons is greater than the rate of substitutions in introns for eukaryotic protein coding genes.
5) Evaluate the following statement. An answer of True or False is worth zero points. Justify your answer using an explanation. Exon duplications that occur in the Bacterial genome can produce additional functional domains.