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Describe three distinct molecular mechanisms

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Describe three distinct molecular mechanisms whereby cells can acquire selfsufficiency in growth signaling. Give one specific example for each mechanism (i.e. growth factor X does Y in cancer Z).

Most anti-proliferative signals depend on the activity of which protein? What posttranslational modification is involved in controlling the activity of this protein? Describe three distinct molecular mechanisms whereby the signaling circuit that governs this protein may be disrupted in tumor cells.

Reference no: EM131657653

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