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Question - Ethylene glycol (EG) is a well-characterised metabolic poison that causes considerable harm to humans and animals and can lead to fatalities. EG interferes with mammalian alcohol metabolism.
i) Briefly describe how alcohol dehydrogenase (ADH) participates in EG toxicity, include the names of the toxic products that are formed and, generally, how the accumulation of these toxic products can lead to life-threatening situations.
ii) Imagine you are medical professional working in the Accident & Emergency department in a major hospital. Briefly describe the treatment options and how you would treat a patient that presents with EG poisoning?
iii) EG acts as an enzyme inhibitor; that is a molecule that binds to an enzyme and affects its normal mechanism of action and its normal activity. At the level of the enzyme ADH, which type of reversible enzyme inhibition is utilized in the effective treatment of EG poisoning?
Ammonia NH3 chemically reacts with oxygen gas O2 to produce nitric oxide NO and water H2O. Explain what mass of nitric oxide is produced by the reaction of 7.3g of oxygen gas
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aluminum sulfate solution with water to a final volume of 1.450 L. Calculate the number of moles of aluminum sulfate before dilution.
Problem- Before the industrial revolution, the concentration of CO2 in the Earth's atmosphere was about 275 ppm. Considering the effect of dissolved CO2 only, calculate the effect that the increase in CO2 has had on the pH of precipitation.
By how much must an enzyme reduce the activation energy of a reaction at 37°C in order for the reaction to occur 100 times faster than in the absence of the enzyme?
How do you rank compounds in order of increasing/decreasing phosphoryl group transfer potential. How do you tell which one has the highest potential
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Solid ammonium chloride, NH4CI reacts with solid sodium hydroxide to produce ammonia gas, water and sodium chloride NaCl
Use Coulomb's law to calculate the ionization energy in kJ/mol of an atom composed of a proton and an electron separated by 278.00 pm then, What wavelength of light would have sufficient energy to ionize the atom
Problem- For each pair below, write a balanced equation showing what happens when the two compounds are combined. If there is no reaction, show the solvated ions that result in the solution.
Which intermolecular force or bond is responsible for the high boiling point of NH3 relative to PH3 and AsH3? a. hydrogen bonding
For the molecule shown below, choose all the statements that are true. Soluble is where at least 10 drops of the compound can be added to a particular solvent (in this case, water or hexane -- CH3CH2CH2CH2CH2CH3) and the result is one homogeneous ..
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