Reference no: EM133343868
Hypersensitivity
• Summarize genetic and environmental factors that influence allergy development.
• Outline the steps of a type I allergic response, and discuss the effects on target organs and tissue.
• Identify three conditions caused by IgE-mediated allergic reactions.
• Describe the symptoms of anaphylaxis and link these to physiological events.
• Briefly describe two methods for diagnosing allergies.
• Explain the mode of action of two strategies for treating and preventing type I allergic reactions.
16-2: Type II Hypersensitivity
• List the three immune components causing cell lysis in type II hypersensitivity reactions.
• Explain the molecular basis for the ABO blood groups, and identify the blood type of a
"universal donor" and the blood type of a "universal recipient."
• Explain the role of Rh factor in hemolytic disease development and how the disease is prevented in newborns.
16-3: Type III Hypersensitivity
• Identify commonalities and differences between type II and type III hypersensitivities.
• Describe the ways in which the Arthus reaction differs from serum sickness.
16-4: Type IV Hypersensitivity
• Identify one type IV delayed hypersensitivity reaction, and describe the role of T cells in the pathogenesis of this condition.
• List four classes of grafts, and explain how host versus graft and graft versus host diseases develop.
16-5: Autoimmune Disorders
• Outline at least three different explanations for the origin of autoimmunity.
• Identify the autoimmune diseases, and describe immunologic features common to all.
16-6: Immunodeficiency
• Distinguish between primary and secondary immunodeficiencies, explaining how each develops.
• Define severe combined immunodeficiency, and discuss current therapeutic approaches to this type of disease.
• List three conditions that can lead to the development of secondary immunodeficiency diseases.