Describe the stages of graft rejection

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Describe the stages of graft rejection - hyperacute, acute and chronic; focus on causes and overall effect. (That's the question) Your answer should address the following

  • The type of immune cell(s), major immune molecules involved (note: you can keep it a bit general. Antibodies are fine, you don't have to get more specific; cytokines are fine, you don't have to name individual ones. Focus on immune cell types we talked about in the course).
  • The timing of the rejection response (right away? after a few weeks, months, years?)
  • For each of the stages, can the rejection response be treated? (is there a medication, etc. that makes the response less likely to happen or treats the response). 
  • Transplant responses normally involve T-cells (most stages, not all). For each of the stages, are T-cells playing a major role? If so, is the antigen presenting cell from the patient (recipient) or from the tissue donor (see the linked article above for a good diagram of this).

Reference no: EM132486662

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