Reference no: EM13912445
1. You are using a packed bed reactor to perform an enzymolysis step (S ® P). The catalyst particles are non-porous and spherical, and the enzyme is bound to the external surface. The particles are 6 um in diameter, and the void spacing of the packed bed is 0.8. If the cylinder housing is 2 inches in diameter, determine how long the reactor needs to be for 80% of the substrate to be converted to product at a flowrate through the column of 500 ml/min. Note: assume the mass transfer coefficient for the column at 500 ml/min is 5 x 10-8 m/s.
2. In working with the packed bed reactor in problem 1 above, you notice that the reactor behaves the same (i.e. product concentration leaving the reactor) regardless of the viscosity of the fluid flowing through it.
a.) Does equation 10-64 from your class notes accurately describe the reactor performance? Why or Why not.
b.) Assume that the kinetics for the immbolized enzyme in this reactor limit the production of P (not mass transfer, as in question 1 above), and that the kinetics take on the standard Michaelis-Menton form:
(V (mol/m2s) = Vm"[S] / Km + [S]
With Vm" defined per unit of catalyst surface area
Derive an expression for Concentration of substrate versus the length of the packed bed reactor as a function of (Vm", Km, εb, a, U, dp and CA0).
c.) Use the values given in problem 1 above. Assume that the reactor is NOT limited by mass transfer. Assume that Km = 0.001 mol/l, that CA0 = 1 mol/l. Using the reactor length calculated in problem 1, determine the Vm" (mol/m2s) value necessary to convert 80% of the substrate to product in the reactor.
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