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Describe the process of clot dissolution

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Question

Hemostasis

1. Describe the following mechanisms:

a. vascular spasm b. platelet plug formation c. blood coagulation

2. What triggers each of the mechanisms listed above?

3. What are platelets? What cells give rise to them? Which of the chemical released by platelets function in vasoconstriction and/or platelet activation? What cells are stimulated to divide by PDGF?

4. Why is blood clot formation referred to as the clotting cascade?

5. Where are most of the clotting factors synthesized?

6. What triggers the intrinsic and extrinsic pathways of blood clot formation? What is the end product of these pathways?

7. Outline the events of the common pathway of the clotting cascade.

8. Describe the process of clot dissolution (fibrinolysis).

9. What intrinsic factors/features function to prevent inappropriate blood clotting? Give examples of several natural and pharmaceutical anticoagulants.

Reference no: EM133426537

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