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Describe the metabolism of ifosfamide in comparison to cyclophosphamide using structures and a short paragraph. Which one would you expect to be more toxic (350 words)fosfamide and cyclophosphamide. Both share the same mechanism of action by alkylating DNA but their metabolism is different. You will have to do some research to investigate the metabolic routes, especially the involved enzymes, to determine if and which drug is more toxic.
Choose a newly introduced anti-neoplastic agent that is derived from a marine natural source and describe briefly its mechanism of action, metabolic pathways, and toxic side effects( 350 words) This question asks you to investigate a growing and diverse resource for drug discovery - marine natural products that have been found to be potential new lead drugs for chemotherapeutic agents. Pick one such drug and describe its structure, mechanism of action, and if it could serve as a potential lead for clinical investigations.
As new technologies have emerged, the variety of available channels of communication has grown dramatically. Discuss the new technology-enhanced channels for public relations and how they have affected the discipline.
A score that is 6 points below the mean corresponds to a z-score of z = -0.50. What is the population standard deviation? Show work.
explain how popular culture has no fixed forms. what does this mean? given the problematic nature of studying popular
conduct a critique of one blog one video and one podcast which provide information that addresses the topic of your
correlation does not imply causation is a phrase that emphasizes that correlation between two variables does not
In a population of exam scores, a score of X = 48 corresponds to z = +1.00 and a score of X = 36 corresponds to z = -0.50. Find the mean and standard deviation for this population.
Manganese ions block the calcium channels in the cardiac muscle membrane. How would the presence of manganese in the extracellular fluid affect the contraction of the heart muscle?
How is sleep apnea considered by some to be a social disease? Explain the rationale. How does sleep apnea differ from common snoring
According to Plato, what are the three parts of the soul? Which part should “rule” over the others, and why? Can you think of an example in your own experience when the parts of our soul (in Plato’s sense) were in conflict rather than in a harmonious..
Describe a specific aspect you see in the art and/or architecture of Ravenna that reflects Augustine’s views of Christianity found in Confessions and The City of God.
A child is told that Bob is older than Sally, and Sally is older than Fred. When enquired, "Who is older, Bob or Fred?" child replies, "Bob." This child is demonstrating __________ ability.
The article title “Is Business Bluffing Ethical?” by Albert Z. Carr. It argues that business ethics essentially are the ethics of a game, particularly poker, and that they differ significantly from the ethics of private life. Game ethics, maintain Ca..
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