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Describe the immunopathogenesis of the joint changes

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A 30-year-old woman recently diagnosed with rheumatoid arthritis (RA) complains of general fatigue and weight loss along with symmetrical joint swelling, stiffness, and pain. The stiffness is more prominent in the morning and subsides during the day. Laboratory measures reveal an elevated rheumatoid factor.

a. Describe the immunopathogenesis of the joint changes that occur with RA.

b. How do these changes relate to this woman's symptoms?

c. What is RF and what is the significance of her RF test results?

d. How do her complaints of general fatigue and weight loss relate to the RA disease process?

Reference no: EM132383436

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