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Question 1: The Neurobiology of Addiction
Background: Many addictive substances can lead to changes in dopamine levels in the brain. For example, both cocaine and alcohol are associated with elevated levels of baseline striatal dopamine. Although other neurotransmitter systems have been implicated, there is strong evidence that substance addiction primarily involves the dopamine (dopaminergic) system. The dopaminergic system also seems to play a key role in behavioural addictions, especially pathological gambling.
Readings:
van Holst et al. (2018)- 10.1016/j.biopsych.2017.06.010
DSM-V (2013) criteria for Pathological Gambling,
Nutt et al. (2015)- 10.1038/nrn3939
Provide a very clear description of the dopaminergic system and its key functions. Comprehensively and clearly describe pathological gambling, including the behaviours and feelings involved. Provide relevant contextual information about the Holst et al. (2018) study and considers the potential implications of the findings. Be very clear and concise in nature.
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