Reference no: EM133424467
SECTION A
Questions
1. Describe the mechanism of action for DOBUTAMINE.
2. Majority of drugs bind to specific receptors on the surface or interior of cells, but there are many other cellular components and non-specific sites which can serve as sites of drug action. Describe at least FIVE of these components.
3. Explain the THREE major determinants of distribution of drugs between the plasma (central compartment) and extravascular space (peripheral compartment).
4. Explain the first pass effect in pharmacokinetics.
5. What are the two types of adaptive immunity, and what types of microbes do these adaptive immune responses combat.
6. How do the different components of innate immunity function to combat different types of microbes?
7. Explain how microbes evade the innate immune system.
8. List at least FOUR examples of drug categories that may decrease appetite.
9. Using examples, explain the nutrition implications of excipients in drugs.
10. Clinicians including dietitians should obtain a full drug and diet history including the use of OTC and dietary supplements and review potential drug-food interactions. Discuss why this is important.
SECTION B
Questions
1. Explain how dose, bioavailability, rate of absorption, apparent volume of distribution, total clearance, and elimination half-life affect the plasma concentrations of a drug after administration of a single dose.
2. Explain the role of vitamins A, B complex, C, D and E in immunity.
3. Describe the general rules of innervation in the autonomic nervous system.