Depression with specific medication

Reference no: EM133707184

Question

A patient is being treated for depression with a specific medication. The pharmacokinetic profile of this medication reveals a dissociation constant (Kd) of 344 pg/mL and an effective dose for 50% of the population (ED50) of 200 pg/mL. What can be inferred from these pharmacokinetic parameters? The drug's high Kd value indicates it has a very high binding affinity. The drug requires full receptor saturation to be effective, as indicated by the Kd and ED50 values. An ED50 lower than Kd suggests the drug is ineffective. The presence of spare receptors can be inferred from these values. The medication is likely to cause severe side effects due to high potency.

Reference no: EM133707184

Questions Cloud

Hands and feet due to diabetic neuropathy : This client has diabetes and often feels numbness and tingling in their hands and feet due to diabetic neuropathy.

While legal in many states and countries : This topic has evolved significantly over the years, and remains to this day a controversial one. While legal in many states and countries,

Evaluates the appropriateness of the physical resources : Manages and evaluates the appropriateness of the physical resources to provide, effective, efficient, safe ethical care, recognizing and reporting situation

Parents regarding starting antidepressant therapy : A primary care provider is talking with an adolescent patient and his parents regarding starting antidepressant therapy.

Depression with specific medication : A patient is being treated for depression with a specific medication. The pharmacokinetic profile of this medication reveals a dissociation constant

Why glomerular filtration rate is index of kidney function : Explain in your own words why glomerular filtration rate is the best index of kidney function.

Pros and cons of private vs public healthcare insurance : Identify the pros and cons of private vs public healthcare insurance. Address how each is financed and how this related to health policy (pros and cons)

About administering vaginal suppositories : What does the nurse know to be true about administering vaginal suppositories to an adult?

Describe the target population : Describe the target population. Describe the specific behavior to focus on in the health communication campaign

User Account

All Pages