Depression with specific medication

Assignment Help Science
Reference no: EM133707184

Question

A patient is being treated for depression with a specific medication. The pharmacokinetic profile of this medication reveals a dissociation constant (Kd) of 344 pg/mL and an effective dose for 50% of the population (ED50) of 200 pg/mL. What can be inferred from these pharmacokinetic parameters? The drug's high Kd value indicates it has a very high binding affinity. The drug requires full receptor saturation to be effective, as indicated by the Kd and ED50 values. An ED50 lower than Kd suggests the drug is ineffective. The presence of spare receptors can be inferred from these values. The medication is likely to cause severe side effects due to high potency.

Reference no: EM133707184

Questions Cloud

Hands and feet due to diabetic neuropathy : This client has diabetes and often feels numbness and tingling in their hands and feet due to diabetic neuropathy.
While legal in many states and countries : This topic has evolved significantly over the years, and remains to this day a controversial one. While legal in many states and countries,
Evaluates the appropriateness of the physical resources : Manages and evaluates the appropriateness of the physical resources to provide, effective, efficient, safe ethical care, recognizing and reporting situation
Parents regarding starting antidepressant therapy : A primary care provider is talking with an adolescent patient and his parents regarding starting antidepressant therapy.
Depression with specific medication : A patient is being treated for depression with a specific medication. The pharmacokinetic profile of this medication reveals a dissociation constant
Why glomerular filtration rate is index of kidney function : Explain in your own words why glomerular filtration rate is the best index of kidney function.
Pros and cons of private vs public healthcare insurance : Identify the pros and cons of private vs public healthcare insurance. Address how each is financed and how this related to health policy (pros and cons)
About administering vaginal suppositories : What does the nurse know to be true about administering vaginal suppositories to an adult?
Describe the target population : Describe the target population. Describe the specific behavior to focus on in the health communication campaign

Reviews

Write a Review

Science Questions & Answers

  Journal of pharmaceutical sciences

This journal is a scientific publication of Indian Pharmaceutical Association and highlights various bright points of it.

  Optical fibres

This document discuss about the main attributes and characteristics of optical fibres.

  Micro organisms

This project report reveals the fact and proves a specific objective mentioned to be studied upon.

  Describing histology of an organ

The discussion of the technique should include a literature review on the evolution of the technique.

  Interpret the sensitivity of mammography

Calculate and interpret the sensitivity of mammography. Diagnostic test with Sensitivity 50%, Specificity 50% and prevalence 50%. Crude mortality rate. Damage caused by motor vehicle accidents.

  Discuss the role that science plays in your daily life

Role that science plays in your daily life and Integrity, Intensity, Innovation, and involvement in scientific field

  Prepare a flexible budget gator divers

Prepare a Flexible Budget Gator Divers is a company that provides diving services such as underwater ship repairs to clients in the Tampa Bay area.

  Neurological disorders

Designing a neuroprosthesis for the neurological disorders

  Complexity of cell surfaces

Lipid rafts provide another example of the complexity of cell surfaces in both their structural character and biologic functionality. Please explain the nature of these structures and their functionality.

  Exploratory activity on bird beaks

Describe how natural selection and evolution are demonstrated by this activity

  Spatial and temporal variation of heat content in the upper

In this study the temporal and spatial variation of heat content in the upper 70m layer of the Arabian Sea was for a period of 1991 to 2008 have been attempted.

  Earthquake databases

Earthquake Databases

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd