Define how the designed sensing strategy functions

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Reference no: EM13214264

Molecular beacons have been used extensively for the detection of nucleic acids and are suitable for analyses in vivo. Recently, hospitalization of hundreds of people in the developing world has resulted from a waterborne viral infection known as the Coxsackievirus B6 (CVB6). A new molecular beacon has been proposed by Yeh et al. and uses a quantum dot - gold nanoparticle based FRET system to signal hybridisation of the molecular beacon to a CVB6 specific nucleic acid sequence. Yeh, H-S.; Yates, M.V.; Mulchandani, A.; Chen, W. Chem. Comm. 2010, 46, 3914-3916.

(a) explain how the designed sensing strategy functions. Point form answers are acceptable, feel free to use a diagram in your explanation.

Reference no: EM13214264

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