Reference no: EM133245500
Assignment:
Questions
1. Define hematopoiesis, erythropoiesis, leukopoiesis, and thrombopoiesis.
2. Differentiate between medullary and extramedullary hematopoiesis.
3. Name one site of hematopoietic tissue and what role it plays in hematopoiesis and/or homeostasis.
4. Discuss the function of the spleen.
5. Define the terms erythrocyte, platelet, thrombocyte, granulocyte, megakaryocyte, leukocyte, monocyte, and lymphocyte.
6. Select one of the following (erythrocyte, platelet, monocyte, eosinophil, basophil, neutrophil, and lymphocyte) and identify the cells in hierarchical order of elaboration beginning with the pluripotential stem cell and concluding with the mature cell.
7. Recall the source of mast cells, macrophages, and plasma cells.
8. Describe the role of erythropoietin in controlling the rate of production of red blood cells.
9. Define the myeloid to erythroid ratio
10. Describe general cellular characteristics for each of the following: size, nuclear/cytoplasmic ratio, nuclear characteristics, nuclear shape, presence of nucleoli, cytoplasm characteristics, shape. (i.e., the larger the size of the cell, generally the more immature it is, and continue to do the same for the remaining characteristics)
11. List the components of a complete blood count
12. Discuss RBC indices in terms of calculation and use
13. Discuss the "rule of threes" in the correlation of Red Cell values
14. List the factors involved in the production of erythrocytes and the role each factor plays in erythropoiesis.
15. Describe the structural changes in the formation of the erythrocyte from the pluropotential stem cell through maturation
16. List the RBC stages using the CAP nomenclature.
17. Describe normal erythropoiesis in terms of the following factors: site of formation; mitosis; maturation time; erythrocyte destruction sites
18. Discuss the shape, size, life span, make-up, and function of the mature erythrocyte.
19. Describe the structure and function of the normal hemoglobin molecule
20. Define the following terms and recall how each affects the RBC count: aplasia, hypoplasia, hyperplasia, pancytopenia, erythrocytosis, polycythemia, and anemia.
21. Describe the RBC membrane structure and composition
22. Name the red cell metabolic pathways and their contribution to energy production
23. Discuss the relationship of hemoglobin and the oxygen disassociation curve
24. Differentiate the abnormal hemoglobins in terms of oxygen carrying capacity
25. Compare and contrast intra-and extra-vascular hemolysis
26. Recall the reference ranges for RBC count in adult males, adult females, and the newborn.
27. Define Anisocytosis and Poikelocytosis
28. Describe iron needs, absorption, and metabolism.
29. Name the four chemistry tests that make up an iron studies panel.