Define a nucleophilic acyl substitution reaction

Reference no: EM13688504

Problem- The preparation of aspirin is an example of a nucleophilic acyl substitution reaction of the nucleophilic phenol group on the protonated acetic anhydride electrophile.

Write a complete mechanism for this reaction.

Reference no: EM13688504

Questions Cloud

Suggest a structure for the compound : Benzil reacts with 1, 2 diaminobenzene to give a compound with molecular formula C20H14N2. Suggest a structure for this compound and write a reaction mechanism to show how it is formed.

Explain interact with generic humic material : Problem- Look up the structure of the following pesticides and show how they could interact with generic humic material. Atrazine, Fenitrothion, Chlorpyrifos, Chlordane, Chlorothalonil, Aldicarb, Malathion and Trifluralin

How can painting be used to teach descriptive writing : How can painting be used to teach descriptive writing and what are some language arts benefits of using visual arts to teach?

Salicylic acid is both a phenol and a carboxylic acid : Problem- Salicylic acid is both a phenol and a carboxylic acid. 1) Explain why acetylation with acetic anhydride occurs at the phenolic hydroxyl group rather than at the carboxyl group.

Define a nucleophilic acyl substitution reaction : Problem- The preparation of aspirin is an example of a nucleophilic acyl substitution reaction of the nucleophilic phenol group on the protonated acetic anhydride electrophile.

Illustrate that charge balance is adequately maintained : Problem- Water from a lake in an area with limestone bedrock has a chemical composition as follows- Calcium 95 mg L-1, Magnesium 12mg L-1, Sodium 17mg L-1, Potassium 4 mg L-1, Hydrogen carbonate (asHCO3-) 338 mg L-1, Sulphate (as SO4-2)7 mg L-1,Ch..

Venus de willendorf with the culture : Outline and Proposal following the annotations, you will be ready to plan your paper. An outline (one and one half pages) and a proposal (two to three pages) of your intended project are due.

Explain the multi-step synthesis : Problem- You work in a small-scale manufacturing facility that uses acetophenone as the starting material for a multi-step synthesis. Your company buys ~98% pure acetophenone from a major manufacturer and purifies it in-house prior to its use in t..

The selective coefficient for calcium over sodium : The water has the following composition in meq/L. The selective coefficient for calcium over sodium is 2.6. Ca2+ 2.2 meq/L Mg2+ 1.0 meq/L Na+ 3.0 meq/L HCO3- 2.9 meq/L Cl- 3.1 meq/L SO4-2 0.2 meq/L

User Account

All Pages