Defects in the intestinal epithelial barrier function

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Defects in the intestinal epithelial barrier function leading to leaky gut that is associated with an increased paracellular permeability might have loss-of-function mutations in which of the following? (Please provide a brief explanation)

a) Connexin

b) integrin

c)claudin

d) cadherin

e) titin

Reference no: EM13250580

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