Creatinine is substance that readily filters

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Questions

1. Outline the intrinsic (myogenic, tubuloglomerular) and extrinsic (renin-angiotensin-aldosterone, neural) mechanisms by which glomerular filtration rate is regulated.

2. Creatinine is a substance that readily filters at the glomerulus, and while none undergoes tubular reabsorption, small amounts undergo tubular secretion. Given that, would you expect the rate of clearance of creatinine to be exactly equal to the GFR? Explain your answer.

Reference no: EM133410090

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