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Question: Consider ABC transporters and their functions. How could an ABC transporter inhibitor be used to make chemotherapy treatments more effective?
• Inhibiting the ABC transporter would reduce ATP consumption, thereby reducing the concentration of toxic free radicals.
• Inhibiting the ABC transporter would promote the efflux of waste to maintain cellular health.
• Inhibiting the ABC transporter would promote the transport of the chemotherapeutic drugs across the cellular membrane.
• Inhibiting the ABC transporter would prevent the efflux of chemotherapeutic drugs, thereby maintaining intracellular chemotherapeutic concentrations.
2. How does the neurosecretory cells demonstrate the overlap between the endocrine and nervous system?
Think about a man who has been exercising. His arterial receptors detect a rise in his blood CO2 and send this information to the brain. He requires to increase both the rate and depth of his breathing.
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