Reference no: EM131538095

In a double blind experiment, long term pain care patients were randomly assigned to either take Embeda (Morphine sulfate and Naltrexone hydrochloride) or Kadian (Morphine sulfate) for a 6 week period, participants were given an appropriate starting dosage of the medication based on their previous therapy dosing determined by their respective physician. Of 24 people given Embeda, 14 were able to manage their pain with the starting dosage at the end of the 6 week, whereas in the Kadian group, only 4 of 24 were able to manage their pain with the starting dosage at the end of the 6 week period. Whether a patient maintains the same dose throughout the 6 week period is of particular importance to researchers, as it suggests the medication is stable/effective for pain management. 

6. Organize these data/results (i.e. frequencies) into a two-way table.

Embeda Kadian Total

Participants stayed on same dosage

Participant dosage increased

Total

1. Compute the proportion of the overall sample (all 48 participants) that maintained the same medication dosage.
2. Of the 24 participants assigned to Embeda, what proportion maintained the same medication dosage? Use correct notation.
3. Of the 24 participants assigned to the Kadian, what proportion maintained the same medication dosage? Use correct notation.
4. Calculate the sample difference in proportions. Use correct notation.
5. Interpret the sample difference in proportions in the context of the study.
6. Calculate the sample relative risk of maintaining the same medication dosage for the Embeda group compared to the Kadian group.
7. Interpret the sample relative risk in the context of the study