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13. The component of the immune system which protects against pathogens without requiring prior sensitization is referred to as:A. HumoralB. CellularC. InnateD. AdaptiveE. All categories require prior sensitization.14. Specific immunity in a person includesA. ingestion of bacteria by phagocytes.B. involvement of helper T cells and B cells.C. development of inflammation around a cut.D. production of lysozymes in tears.15. Situations leading to active immunity include aA. baby receiving antibodies through the placenta prior to birth.B. baby receiving antibodies in the mother's milk one month after birth.C. baby receiving a vaccination against diptheria three months after birth.D. all of the above16. In humans, nonspecific immunity includesA. production of antibodies by plasma cells.B. different responses for different bacteria.C. phagocytosis of bacteria by neutrophils.D. presentation of material to a T cell by a phagocyte.17. Non-specific immunity in mammals includesA. the action of lysozymes in tears and saliva.B. the production of antibodies after infection.C. the production of memory cells.D. the action of T helper cells.18. Antibodies crossing the placenta from mother to fetus is an example of:A. vaccinationB. cell-mediated immunityC. passive immunityD. active immunity19. Which of the following is not true for Antigen Presenting Cells (APS)?A. called Langerhans cells in epidermisB. have same external marker proteins as macrophagesC. have a high concentration of HLA Class II antigensD. all are highly ameboid and phagocytic20. "A", and "B", and "C" HLA proteins are: A. found on all cells of the bodyB. found only on immunocompetent cellsC. essential to complement activationD. phagocytized by activated macrophages21. "A", & "B", & "C", and "DR", & "DP", & "DQ" HLA proteins are: A. found on all cells of the bodyB. found only on immunocompetent cellsC. essential to complement activationD. phagocytized by activated macrophages22. Which of the following is true concerning Natural Killer (NK) cells?A. important in the production of antibodies.B. non-specifically kill virally infected and tumor cells.C. only kill cells after being activated by interaction with APCs.D. they are known as Langerhans cells when found in the thymus23. Complement proteins are capable of:A. activating B cells to produce antibodyB. directing Natural Killer cell activityC. lysing foreign cells that have antibody bound to themD. being presented by APCs24. Which of the following is not true for B-lymphocytes?A. circulate in the bloodstreamB. found in the lymphatic nodesC. develop and mature in the Thymus glandD. capable of differentiating into plasma cells.25. Tumor-cell lysing ability is not seen with which of the following:A. delayed hypersensitivity (Tdth) cellsB. macrophagesC. activated Killer cellsD. cytotoxic T-cells26. Which of the following is least phagocytic?A. neutrophilB. dendritic cellC. macrophageD. plasma cell27. Which of the following does not function as an Antigen Presenting Cell (APC).A. dendritic cellB. reticulocyteC. macrophageD. langerhans cell28. Which of the following is carried out by specialized cells circulating in blood and lymph.A. humoral immunityB. cell mediated immunityC. innate immunityD. the trash29. Which of the following are special immune-system proteins circulating in blood and lymph.A.complementB.MHC Class I proteinsC.antigensD.epitopes30. Which of the following is not an activity of IgA. opsonizationB. complement activationC. viral neutralizationD. antigen processing31. B cell surface-bound antibody is most likely to be:A. IgAB. IgEC. IgGD. IgM32. Which of the following is true for T-lymphocytes?A. highly phagocytic, microbe-killing cellsB. first found in the T-nodes of T-birdsC. originate from stem cells in the Thymus glandD. capable of stimulating or suppressing immune function.33. The normal ratio of CD4:CD8 cells is 2:1. Why does this ratio become inverted in a patient with AIDS.A. clonal expansion of Th cellsB. clonal expansion of Ts cellC. loss of Th cellsD. increase in CD8 cellsMatchingA = true for Class 1 HLA proteinsB = true for Class 2 HLA proteinsC = true for both Class 1 and Class 2 HLA proteinsD = true for neither34. found on all nucleated cells of the body A35. expressed on T cells following activation36. involved in communication between immunocompetent cells37. closely associated with viral protein on surface of virally-infected host cell.38 closely associated with antigen epitope on surface of antigen presenting cell.39. one "set" -comprised of six different protein molecules- three inherited from each parent.40. include complement system proteins.Matching1. Cells which are actively manufacturing antibodies2. Cells which are capable of making antibodies once activated3. Migratory cells capable of presenting antigen4. Cells capable of killing virally infected cells (MHC-restricted)5. Cells capable of killing tumor cells (no MHC-restriction)6. Cells which are capable of stopping the immune response7. WBCs most efficient at phagocytosis and killing of bacteria8. Precursors of platelets9. Immature red blood cells10. Special proteins capable of binding to a specific antigen11. Cells which secrete lymphokines to activate other immunocompetent cells12. IL1 and TNFa, for exampleA. NeutrophilsB. ImmunoglobulinC. Plasma cellsD. ReticulocytesE. LymphokinesAB. MacrophagesAC. MegakaryocytesAD. Natural killer cellsAE. Cytotoxic T cellsBC. Suppressor T cellsBD. Helper T cellsBE. B cells
It is a very curcial concept to understand how the immune response is mounted against viruses, bacteria, protozoans and helminthes. For an effective immune response, both innate and adaptive immunity should work together.
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