Component of flagella in some bacteria

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Individuals with Crohn's disease (CD) have - responses that target - , a component of flagella in some bacteria. Specifically, - are targeted in a large subset of people with Crohn's disease and in mouse models of CD. One hypothesis for the targeting of this relatively minor abundance microbe is that it localizes to a location in the intestine that is proficient at inducing - responses rather than - responses. TH17 Lactobacillus spp. Clostridium spp. TH2 lipopolysaccharide effector regulatory flagellin.

Reference no: EM133610746

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