Compartment drug has plasma half life

Reference no: EM133686401

Question

If one compartment drug has plasma half life 2.5hr, volume of distribution 245L, absorption rate constant 1.03 (1/hr) and oral bioavailability of 25%. The therapeutic window of drug is approximately 10-80ng/ml. If the anesthetic concentration of 50ng/ml is to be maintained for surgery what should be the infusion rate.

Reference no: EM133686401

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