Compare the percentages that had a bad result

Reference no: EM131807126

Question: Multiple Myeloma One treatment for multiple myeloma (cancer of the blood and bones) is a stem cell transplant. However, in some cases the cancer returns. McCarthy and colleagues reported on a study that randomly assigned 460 patients (100 days after a stem cell transplant) to receive either lenalidomide or placebo. At one point in the study, 46 of the patients who received the real drug had a bad result (had progressive disease or had died), compared to 101 of those who received the placebo. Assume that exactly half were assigned to each group.

a. Find and compare the percentages that had a bad result for the two groups.

b. Test the hypothesis that the drug reduced the chance of a bad result compared to the placebo using a significance level of 0.05.

c. The study started in April 2005 and was "unblinded" in 2009 when an interim analysis showed better results with the group taking the drug. After the unblinding, many of the patients from the placebo group "crossed over" to the drug group. Explain what you think "unblinding" means and why this seems like a reasonable thing to do.

Reference no: EM131807126

Questions Cloud

Compare the percentages of death for the two groups : Compare the percentages of death for the two groups descriptively. Which group had patients who were more likely to live?

Decided that the stocks of six firms : An investor has carefully studied a number of companies and their common stock. From his analysis, he has decided that the stocks of six firms

How much increase in income is expected : The fixed costs are $80,000 per year & inventory levels are declining. If sales increase by 10,000 units in coming year, how much increase in income is expected

Compare nestle to a us food company : Discuss the implications of each of these items in terms of the effect - compare Nestle to a US food company such as Kraft Foods and an Australian food company

Compare the percentages that had a bad result : Multiple Myeloma One treatment for multiple myeloma (cancer of the blood and bones) is a stem cell transplant. However, in some cases the cancer returns.

Which alternative should be selected : For an 8% interest rate, which alternative should be selected? Each alternative has a 6-year useful life.

Discuss the differences in classifications of cash flows : Discuss the differences in classifications of cash flows between IFRS and U.S. GAAP. What impacts will these have on U.S. companies?

High-reliability organizations providing long-term care : In this Assignment you will identify major elements of high-reliability organizations providing long-term care.

What is the budgeted total variable cost : Each Colby Steak dinner sells for $22.00 each. What is the budgeted total variable cost

User Account

All Pages