Reference no: EM133418147
A reproductive endocrinologist has the following patients:
Alan is 24 years old, and an Olympic track athlete that has been injecting himself for the past 6 months with a designer kisspeptin agonist that crosses the blood brain barrier. He will continue to take this drug until he is done with his Olympic career in 2 years. This agonist binds the kisspeptin receptor just as well as kisspeptin does, but because it not a known drug, it is not detected in the drug screenings he undergoes. His BMI and percent body fat are in the normal range.
Bob is 26 years of age. He has an undiagnosed mutation in his 11 beta hydroxylase enzyme that is involved in steroidogenesis. He is short in stature and muscular, but his BMI and percent body fat are in the normal range.
Curtis has an LH receptor mutation that renders it nonfunctional. He is 25 years old. Although he is not as muscular as Alan and Bob, his BMI and body fat content are in the normal range.
Doug is 35 years old. He was diagnosed with hormone sensitive breast cancer and started taking a highly (greater than 95% effective) potent aromatase inhibitor a month ago as part of his chemotherapy treatment. The cancer was detected very early and the small tumor was removed successfully and although Doug has never suffered any ill effects from the cancer, and the doctors are sure all cancerous cells were removed he is undergoing chemotherapy as a precaution. His BMI and percent body fat are in the normal range.
Eric is 72 years old. As a former Olympic athlete, he is still incredibly fit and has a BMI and body fat content equal to Alan.
Frank is 23 years old and an Olympic marathon runner. His nutritionist is making sure that his daily caloric intake is just matching his energy expenditures for maintenance and his athletic training so that he remains extremely lean. He has been suffering from some joint inflammation, so he has been taking Cox enzyme inhibitors for the past 3 weeks.
Henry is 27 years old and obese with a BMI of 38.
Ian is 71 years old and Frank's friend. Given Frank's physical condition and robustness, Ian has been taking testosterone supplements for the past year. But, Ian over does it and takes too much because he thinks it makes him feel younger and for the past 8 months his blood testosterone levels have been 2 times greater than the level found in normal 25-year old man. His BMI and percent body fat are in the normal range.
Kevin is 26 years old and works for a pesticide manufacturer. His BMI and body fat content are normal. Unbeknownst to Kevin, at work he is exposed to and absorbs a compound that causes him to produce antibodies that bid the alpha subunit of inhibin preventing it from binding the betaglycan receptor.
Compare and contrast (rank) blood leptin levels between Bob, Curtis, Henry and Ian (explain your answer)