Reference no: EM133201098
Question 1. The appearance of macrocyte red blood cells in blood film preparations are a feature of the following condition(s)?
Liver disease and alcoholism.
Autoimmune hemolytic (haemolytic) anemia, including both warm and cold types. Normal glucose-6-phosphate dehydrogenase (G6PD) gene function.
Iron deficiency.
Sickle cell anemia.
Question 2. Which statements are FALSE regarding β- thalassaemia major?
Results from a dietary lack of Vitamin B12.
Can result in bone marrow hyperplasia.
Can result in secondary issues due to contaminated blood transfusions (ex: Hepatitis C or B) .
Is caused by genetic defects or deletion of a alpha-2 globin gene. Is caused by genetic defects or deletion of a β globin gene.
Question 3. Anemia based disorders can result from defects at several critical points during the production and/or maintenance of RBC. This can include .
Dietary defects that suppresses proper heme (haem) and hemoglobin production.
Genetic defects to the alpha- or beta-globin genes and proteins.
Dietary deficiencies that impact cell cycle and the production of both RBCs and WBCs.
Genetic defects altering the membrane dynamics and shape/size of mature erythrocytes.
All are true.
Question 4. Which ONE of the following statements is TRUE about people that have glucose-6-phosphate dehydrogenase (G6PD) deficiency?
Treatment with anti-malarial drugs such as choloroquine can precipitate acute hemolytic anemia.
All are true.
It usually presents as a chronic or ongoing anemia linked to low dietary iron.
Heterozygote deficiency in the form of genetic mutations provides some protection against types of Clostridium infection.
None are true.
Attachment:- Exam Paper.rar