Reference no: EM133296870

Questions

1. List the three reasons why the citrate cycle is considered the hub of metabolism.

2. List the things that the citrate cycle accomplishes with each turn of the cycle

3. Describe why the citrate cycle is thought of as a metabolic engine and what components are thought of as the fuel, the exhaust and the output of work performed

4. Describe the role of redox reactions in biochemical processes and be able to calculate the ΔGº' using reduction potentials from the two conjugate pairs.

5. Explain the importance of the vitamins niacin, riboflavin, pantothenic acid, and thiamine to the pyruvate dehydrogenase (PDH) reaction and at which step each is required

6. Describe the causes of pellagra and how this impacts the PDH reaction; describe the biochemical basis for arsenic inhibition of the PDH reaction and citrate cycle reactions.

7. List the eight reactions of the citrate cycle and described them as either exergonic or endergonic.

8. Identify the steps of the citrate cycle in which NADH, FADH2 , CO 2 , and GTP are produced and write the net reaction of the eight citrate cycle reactions.