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1. If a human gamete possessing one extra chromosome participates in fertilization with a normal human gamete, what will be the result? How many chromosomes will the zygote have?
2. If a human gamete that is missing a chromosome participates in fertilization with a normal human gamete, what will be the result? How many chromosomes will the zygote have?
3. If nondisjunction occurs in humans for one pair of homologous chromosomes during meiosis I, will any normal gametes result? How many chromosomes will each gamete have? Explain.
4. If nondisjunction occurs in humans for sister chromatids of one chromosome during meiosis II, will any normal gametes result? What chromosome number would each gamete have? Explain.
5. Many genetic disorders are caused by errors (mutations) in the genes on our chromosomes. Usually, in disorders caused by chromosomal abnormalities, the genes themselves are not mutated; rather, there are too many or too few of them. Why do you think that having too many or too few normal genes creates disorders?
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