Chemistry of proteins and hemoglobin1 protein a has a

Assignment Help Chemistry

Reference no: EM13357110

Chemistry of Proteins and Hemoglobin.

1. Protein A has a binding site for ligand X with a Kdof 10-6M. Protein B has a binding site for ligand X with a Kdof 10-9M. Which protein has the higher affinity for ligand X?

2. What is the effect of the following changes on the O₂ affinity of hemoglobin? (a) A decrease in the blood pH from 7.4 to 7.2. (b) A decrease in the partial pressure of CO2in the lungs from 6 kPa (holding one\'s breath) to 2 kPa (normal). (c) An increase in the BPG level from 5 mM (normal altitudes) to 8 mM (high altitudes). For (c), also consider fetal hemoglobin.

3. Under appropriate conditions, hemoglobin dissociates into its four subunits. The isolated α subunit binds oxygen, but the O₂-saturation curve is hyperbolic rather than sigmoid. In addition, the binding of oxygen to the isolated α subunit is not affected by the presence of H₊, CO₂, or BPG. What do these observations indicate about the source of the cooperativity in hemoglobin?

Reference no: EM13357110

Questions Cloud

Compute the structural analysis of the protein1nbspwhat : compute the structural analysis of the protein.1.nbspwhat order will the following proteins elute from a caution

Periodicity in the ionization energy and balancing the : periodicity in the ionization energy and balancing the equation.1.nbspnbspnbspnbspnbspnbspnbsp rank the

Critical article reviewreference gray a elbroune d dezateux : critical article reviewreference gray a elbroune d. dezateux c king a quinn a gardner f and the united kingdom

Estimating the thickness of a membrane by using bond : estimating the thickness of a membrane by using bond distance.the carbon-carbon bond distance for single-bonded carbons

Chemistry of proteins and hemoglobin1 protein a has a : chemistry of proteins and hemoglobin.1. protein a has a binding site for ligand x with a kdof 10-6m. protein b has a

Find the amount of known substance present in the mixturea : find the amount of known substance present in the mixture.a mixture of calcium carbonate and calcium oxide that weighed

Nbspcritically explain cost accounting as1 a service : nbspcritically explain cost accounting as1. a service activity2. a descriptiveanalytical discipline3. an information

Properties of subatomic particles1 fill in the missing : properties of subatomic particles.1. fill in the missing relative masses and relative charges for each of the subatomic

Individual assignment leadership and transformation an : individual assignment leadership and transformation an important aspect of a graduate education is the ability to

User Account

All Pages