Changes in the integrity of desmosomes

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1. The upper layers of the skin constantly slough off. Predict the changes in the integrity of desmosomes as skin cells age (and move closer to the skin's surface).

2. What would the advantages be for tissues to avascular (like epithelium and cartilage), when their cells depend on the nutrients in blood to be alive?

3. After a year's time in the International Space Station, astronaut Mark Kelly had a complete medical exam, including bone density tests. They revealed decreased bone mass. Is this surprising, since he exercised regularly in the ISS? Will he recover? Explain.

4. Curare is a chemical that can bind to ACh (acetylcholine) receptors and block Ach attachment. Curare (or a derivative) is given prior to tracheal intubation. What effect do you think curare has on the muscle of the larynx (located just above the trachea), and why do you think it is used in tracheal intubation?

5. A patient taking diuretics comes to the clinic complaining of muscular weakness and fatigue. Diuretics cause the body to produce more urine, which will also cause the loss of some ions. A deficiency of which ion will be suspected?

6. As Craig stepped onto the sailboat, he smelled the salty sea air and felt the boat rocking beneath his feet. After a few minutes, the smell faded but he was aware of the rocking motion for the entire sail - four hours. What types of receptors are involved and smell and the detection of motion? Why did the sensation of smell fade but the rather unpleasant sensation of rocking persist?

Reference no: EM132597989

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