Cardiac arrest is treated with fosphenytoin

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A patient in status epilepticus (SE) after a cardiac arrest is treated with fosphenytoin. The patient is currently undergoing targeted temperature management (TTM) for 24 hours to 33° Celsius. Which TTM physiologic change will impact the antiseizure medication concentrations? Increased absorption Decrease renal clearance Decreased hepatic metabolism TTM does not impact these concentrations.

Reference no: EM133815140

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