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Calculate therapeutic index using inhibitory concentration

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Q1. Define the following pharmacological terms: dosage, micrograms, minimum inhibitory concentration, toxic dose, achievable level, therapeutic index.

Q2. Define the following terms: sensitive, intermediate, resistant. Explain how a Kirby-Bauer Antibiotic Susceptibility Test is done, and how it will demonstrate a bacterial species reaction to antibiotics. Explain how you measure zones of inhibition.

Q3. Calculate therapeutic index using minimum inhibitory concentration and toxic dose data. Be able to show the calculation.

Q4. List the 5 cellular areas in which antibiotics destroy the bacterial cell. Give an example of an antibiotic group for each target.

Reference no: EM131723333

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