Reference no: EM1321061

Question: Multiple myeloma or blood plasma cancer is characterized by increased blood vessel formulation in the bone marrow that is a prognostic factor in survival.  One treatment approach used for multiple myeloma is stem cell transplantation with the patient's own stem cells.  The following data represent the bone marrow micro vessel density for a sample of seven patients who had a complete response to a stem cell transplant as measured by blood & urine tests.  2 measurements were taken:  the first immediately prior to the stem cell transplant, & the second at the time of the complete response.

Patient	1	2	3	4	5	6	7
Before (x)	158	189	202	353	416	426	441
After (y)	284	214	101	227	290	176	290

Perform an appropriate test of hypothesis to determine if there is evidence, at the .05 level of significance, to support the claim that the mean bone marrow micro vessel density is higher before the stem cell transplant than after the stem cell transplant?  Calculate the value of the sample test statistic?

[A]   t = 2.7234

[B]   p = 2.7234

[C]   z = 1.8424

[D]   t = 1.8424