Calculate the risk ratio with the misclassification

Assignment Help Other Subject

Reference no: EM133291997

The following questions are about a study that is interested in the relationship between obesity (exposure) as defined by a BMI cutoff of >30, and incident hypertension (outcome). Assume that the BMI gathered for that study are subject to information bias because investigators relied on self-reported height and weight to calculate BMI in the study. The following questions consider the impact of this measurement error of the exposure on study findings.

The following 2x2 table includes the data from your study on the relationship between obesity (exposure) and incident hypertension (outcome); this table represents the misclassified table; that is, BMIs reported with information bias are used. Calculate the risk ratio for incident hypertension among individuals with obesity as compared to individuals without obesity.

	YES incident HT	NO incident HT	Total
Obese	40	14	54
Non-obese	16	42	58
Total	56	56	112

Construct a new 2x2 table under the scenario that 20% of participants with true obesity under-estimated their BMI which lead them to be categorized (incorrectly) as non-obese in the study data; this table represents the true data. Assume that persons who were classified as obese correctly reported their BMI to study investigators. Based upon this "truth" table, calculate the risk ratio for incident hypertension among individuals with obesity as compared to individuals without obesity.
In your table for question #6, draw arrows between the cells to reflect how people are migrating between the cells of your 2x2 table (from truth to misclassified) due to this exposure measurement error. Is this non-differential or differential exposure measurement error?
Given the movement between the cells, explain the differences in the observed risk ratio (from question #5) vs. the true risk ratio (from question #6).

The outcome data on hypertension represents the truth regarding incident hypertension given the great lengths investigators went through to collect this data (measured blood pressure, questionnaire data, and medication information). Consider the scenario whereby investigators instead, due to lack of funding, had to eliminate in-person follow-up visits and relied upon telephone contacts to determine hypertension status through only questionnaire information. As a result, new hypertension cases were missed; among individuals with obesity, 30% of true incident hypertension cases were not reported and among individuals without obesity, 50% of incident hypertension cases were not reported.

How would your 2x2 table look under this scenario? Calculate the risk ratio with the misclassification under this scenario.
Draw arrows between the cells to reflect how people are migrating between the cells of your table (from truth to misclassified) due to this outcome measurement error? Is this differential or non-differential misclassification?
Given the movement between the cells, explain the differences in the misclassified risk ratio (from question #9) vs. the true risk ratio (from question #5). For the purposes of this question, ignore the exposure misclassification from above and consider the table from question #5 as your true table.

Reference no: EM133291997

Questions Cloud

What is game day operations : What is game day operations? Why is it important? Please describe the difference between a regular Home Football game vs. a Homecoming game compare.

Histories of dress and museum collections : Why do you think histories of dress (books) and museum collections (actual garments) are important sources about cultures and their scale?

Identify the psychological principles that are involved : Identify the psychological principles that are involved in the pursuit of the healthy behaviors you selected and explain the ways in which these factors can

What was the cumulative incidence of diabetes from 1991 : HESC 401 California State University, Fullerton In the group that was eligible for study, what was the cumulative incidence of diabetes from 1991 to 1997

Calculate the risk ratio with the misclassification : NUR MISC University of Michigan, Draw arrows between the cells to reflect how people are migrating between the cells of your table (from truth to misclassified)

What is denotation of object : What is denotation of object? What are connotations of your object? Comment on how you think-feel about uncovering complexity of your previously "simple object"

Write a essay employee empowerment : Write a essay on the topic "Employee Empowerment: A Determinant of The Levels of Employee Turnover Within Hospitality".

Describe the current market opportunities for new product : Target Customers- describe the targeted consumers of the launching of the new product/service of streaming platform.

Discuss the stakeholders you would partner : Explain similarities and differences in how you would evaluate these programs. Discuss the stakeholders you would partner with in the evaluation process

User Account

All Pages