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A randomized clinical trial was designed to test the efficacy of a new serotonin re-uptake inhibitor (anxiety reducing drug - ARD) to treat the symptoms of anxiety compared to a more traditional approach of behavioral therapy. The trial randomized 1,200 men and women with untreated anxiety symptoms in a 1:1 ratio to either 1) treatment with ARD, and 2) weekly behavioral therapy sessions. The primary endpoint was resolution of anxiety based on results from a validated anxiety assessment instrument. At six months of follow-up it was found that 200 persons in the ARD group and 50 in the behavioral therapy group met the primary endpoint.
1. Calculate the relative risk of anxiety symptoms for persons in the behavioral therapy group compared to those taking ARD. State your results in a sentence.
2. Calculate the efficacy (as risk reduction) of ARD compared to behavioral therapy. State your results in a sentence.
3. How many patients with untreated anxiety would you need to treated with ARD (instead of behavioral therapy) to resolve the symptoms of anxiety over 6 months?
4. In performing the analysis, it was discovered that men responded better to ARD than women, but they had similar responses to behavioral therapy. Also, the majority of subjects in the study were women. How might this affect your results? Can you suggest a study design that might improve the validity of your
assume you are building a system aircraft etc. for a customer but using the best technology available. you cannot
Inverse relationship with wage spending. What should the microeconomist who developed this multiple regression model be particularly concerned with?
for the high school outreach project that i direct i would like to know if we are having any impact on the high school
In problem, assume that 3 million out of 18 million users could not use their devices as cellphones, and that 1 million could not use their devices.
1. For the standard normal distribution, compute Z0.03. Use Excel and round the answer to two decimal places.
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Atlanta Company stock is expected to follow an exponential growth rate. The relationship between the current stock price P0
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If you estimate a regression using OLS, but you do not include an intercept, do you know if the mean of the residuals is zero? Explain.
What is his expected cash balance at the end of the following May and what is the probability that his balance will be negative in one or more month?
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