Reference no: EM13995701
Incidence Density
A cohort study (hypothetical) was conducted to look at survival after experiencing a myocardial infarction (heart attack). Ten participants were followed for 3 years, resulting in the following table:
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Follow-up Time (Months)
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Event
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3
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Death
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5
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Censored
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8
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Death
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12
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Death
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17
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Censored
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19
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Censored
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27
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Death
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32
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Censored
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36
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Followed until end of study period
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36
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Followed until end of study period
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1) What is the cumulative survival probability at the end of the follow-up period?
2) Using the same data, calculate the overall death rate per 100 person-years.
3) Calculate the rates separately for the 3 years of follow-up.
4) Is it appropriate to report an overall 3-year death rate for this study? Why or why not?
Attributable Risk
A hypothetical cohort study looked at the association between family history and the risk of developing Alzheimer's disease. The results were as follows:
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Alzheimer's Disease
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No Alzheimer's Disease
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Totals
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Incidence of AD
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Family History
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50
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1,950
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2,000
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25 per 1,000
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No Family History
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25
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2,975
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3,000
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8.3 per 1,000
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Total
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75
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4925
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5000
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5) Calculate the attributable risk for Alzheimer's disease due to family history. Interpret the calculation in words.
6) Assume the prevalence of family history in the general population is 5%. Calculate the population attributable risk and interpret it in words.
Now assume the prevalence of family history in the general population is 25%. What effect does this change have on the estimate of the population attributable risk? Discuss the relationship between the population prevalence of exposure and the population attributable risk. Why is it important to understand this relationship as a public health professional?
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Application of sensitivity analysis
: An important application of sensitivity analysis occurs in problems involving multiple attributes. Many decision makers experience difficulty in assessing trade-off weights.
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Problem regarding the various possible loss scenarios
: Compare the grower's expected values for the three alternatives he has, considering the various possible loss scenarios for the burners and the sprinklers. Which alternative would you suggest the grower take? Why?
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Development of a requisite decision model
: What role does sensitivity analysis play in the development of a requisite decision model? Explain why the lines separating the three regions in Figure 5.12 all intersect at Point D.
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The following selected transactions relate to investment
: Indicate any amounts that Ornamental Insulation would report in its 2011 balance sheet and income statement as a result of these investments.
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Calculate the rates separately for the 3 years of follow-up
: s it appropriate to report an overall 3-year death rate for this study? Why or why not?
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What is the final pressure of the gas
: A 2.00 mol sample of a diatomic ideal gas expands slowly and adiabatically from a pressure of 5.056 x 105 pascals and a volume of 12.0 L to a final volume of 30 L. What is the final pressure of the gas?
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Problem regarding the decision-analysis course
: There are so many issues to think about, however, that he has a difficult time keep ing them all straight. After hearing about your decision-analysis course, he asks you whether you have learned anything that might help him in his decision. What k..
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Find the forces that the walls a and b exert on the beam
: A 20.0-m -long uniform beam weighing 640 N rests on walls A and B. Find the forces that the walls A and B exert on the beam when the person is standing at a point 3.3 m to the right of B.
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Innovative new food processor
: Johnson Marketing is interested in producing and selling an innovative new food processor. The decision they face is the typical "make or buy" decision often faced by manufacturers. On one hand, Johnson could produce the processor itself, subcontr..
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