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A sample from a crime scene is genotyped for 4 STR markers located on different chromosomes. The genotypes from a DNA sample collected from blood at the crime scene and from two suspects are given below. The population frequencies of STR alleles at each locus are also given (alleles are designated by the length of the DNA repeat).
MCB10ProblemSet2Fall2016Crime scene sample:Marker 1: 102/101 Marker 2: 121/112 Marker 3: 100/100 Marker 4: 132/154Suspect 1:Marker 1: 102/101 Marker 2: 121/112 Marker 3: 100/100 Marker 4: 132/154Suspect 2:Marker 1: 101/101 Marker 2: 112/112 Marker 3: 100/100 Marker 4: 148/154Population Allele Frequencies:Marker 1: f(102)=0.40, f(101)=0.32.Marker 2: f(121)=0.10, f(112)=0.90.Marker 3: f(100)=0.97, f(106)=0.03.Marker 4: f(132)=0.04, f(154)=0.74, f(148)=0.22.(a) Can either of suspects 1 or 2 be excluded as the perpetrator of the crime based solely on their marker genotypes?(b) Calculate the probability of a genotype match at the 4 loci for an individual drawn at random from the population for which the allele frequencies have been specified above.
You measured the purified protein concentration, which is 5 ug/uL. You decided to load 20 ug protein to the gel. How would you dilute your sample?
Which of these can be classified as a mucus membrane? Please explain.
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A repeating polymer with the sequence 5'- GUAGUAGUAGUA...-3' was found to produce only two types of polypeptides in a translation system that uses cellular componants but not living cells. Onle polypeptide consisted of repeating Val and the other ..
Approximately what percentage of the energy of glucose is transferred to storage in ATP as the result of the complete oxidation of glucose to CO and water in cellular respiration.
q1. listing the two macromolecules that have been partially digested by time acid chyme moves into the intestine where
Max's regular exercise regimen has reduced his high blood pressure, allowing him to achieve normal blood pressure on a single antihypertensive medication.
Briefly describe the debate between the theory of spontaneous generation and the theory of biogenesis. Explain how Louis Pasteur's experiment with the S-neck flasks in the 1800s resolved this debate. Include a detailed description of Pasteur's exp..
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Compare and contrast the mechanisms of pathogenicity developed by foodborne enteropathagenic E. coli, Salmonella and Shigella species that cause infections in the human host. Include : adherence, invasion, intracelluler locomotion.
Briefly identify the legal standard used to determine insanity through an evaluation. What psycholegal questions need to be addressed?
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