Calculate the oxygenated and deoxygenated hemoglobin levels

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Reference no: EM131153600

In the near-infrared region of the optical spectrum between 600-1100 nanometers there are well-known absorbance peaks for oxygenated and deoxygenated hemoglobin. A big assumption can be made for the moment that in this region the dominant optical signal is due to absorption (which is not generally the case). Given that you propagate through a 2-cm sample of tissue, you need to calculate three parameters: the concentration of oxyhemoglobin and deoxyhemoglobin, and a background blood absorbance. At three wavelengths (758 nm, 798 nm, 898 nm), you can measure the extinction coefficients for oxygenated (1.612, 2.072, and 2:763 Mm^-1 cm^-1) and deoxygenated hemoglobin (3.914, 2.072, and 2:072 mM^-1cm^-1), respectively. The total absorption coefficients at these three wavelengths in the tissue can be measured using a time-resolved system as (0:293 cm^-1, 0:1704 cm^-1, 0:1903 cm^-1), respectively. Calculate the oxygenated and deoxygenated hemoglobin levels given these parameters. Is this reasonable from a physiologic point of view? Explain.

Reference no: EM131153600

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