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Suppose that an enzyme uses a catalytic mechanism in which a functional group on the enzyme has to accept a proton from the intermediate formed in the first chemical step. The pKa of that basic functional group on the enzyme is 8.0, and is the only pKa apparent on a plot of kcat vs. pH for the activity of this enzyme. The kcat of the fully active form of the enzyme is 1 x 105 sec–1 .1. Calculate the fraction of the total enzyme active sites in solution that would be in the active form at pH 7.2.2. Calculate what kcat would be if the activity of the enzyme were measured at pH 7.2.
What are some strategies of the anti-retroviral drugs used in the AIDS treatment?
The total pressure of a mixture of water vapor and helium is 0.893atm. The partial pressure of water is 27.3Torr at this temperature. For helium, what are (a) the partial pressure and (b) the mole fraction in this mixture?
Determine the proportion of the lung cancers attributable to smoking among: smokers and the whole population.
What would the CsCl gradient pattern from the Meselson-Stahl experiment look like if replication were fully conservative, that is, if a parental strand gave rise to one daughter with all original DNA and a second daughter with all new DNA?
q1. if a human wants to eat about 10 000 kj per day approximate to the nearest gram the mass of phytoplankton that
What are the causes, symptoms, and complications associated with Type I, Type II, and gestational diabetes (GD)? Compare for similarities and differences.
One haploid strain is unable to synthesize uracil but not unable to synthesize leucine, while another haploid strain is able to synthesize uracil but not leucine.
q1. name the two types of stem cells and explain the main difference between those two types especially in terms of
Injection of double stranded RNA can lead to gene silencing by degradation of RNA molecules complementary to either strand of the dsRNA.
q1. while muscle cells undergo anaerobic respiration they become fatigued and painful. it was once believed lactic acid
Contrast constitutive genes from inducible genes. Give two examples for each.
Hermann Kolbe's synthesis of an organic compound, acetic acid, from inorganic substances that had been prepared straight from pure elements was an important milestone for what reason.What piece of evidence contradicts this claim.
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