Calculate the flux allowed through each pore

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Reference no: EM131409211

The flux F of a molecule present at concentration C through a circular hole of diameter d on a surface that is adjacent to a fluid that it is diffusing in is given by

F = 4DdC

and the total that can be transferred in the per-pore capacity times the number of pores formed.

Calculate the flux allowed through each pore if the diffusion coefficient D is 10^-6 cm²/s, the concentration is 0.1mM and the pore diameter is 1.5nm. With per-pore flux estimated earlier, derive the time constant for transfer of a metabolite from a particular cell to a neighboring cell. Assume that you are dealing with two epithelial cells whose geometry can be approximated as adjacent boxes connected together, with the transfer occurring through n pores.

Reference no: EM131409211

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