Calculate the amount of available t3

Reference no: EM13100354

Chromatographic assay reveals the total amount of T3 in the blood is 10 micrograms. You find that the various bound forms of the hormone are:

T3 (free)= 0.5%

T3 (albumin)= 12%

T3 (TBG)= 69%

T3 (pro-albumin)= 18.5%

Target tissue: heart whose Bmax of T3 receptors= 76 fmol of T3 receptor/mg protein ( 1 fmol=10^-15 mol)

where you have 100 micrograms protein in your heart assay. MW=68kDal

Calculate the amount (in grams) of available T3 and its receptor (also in g). How do the 2 amounts compare? Will Bmax be reached?

Reference no: EM13100354

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