Calculate ratio of bicarbonate to carbonic acid

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Reference no: EM133201112

Question 1.

What appears to be Mary's problem(s), from the results of her blood work? What sort of change has occurred in her acid-base balance? If there is more than one problem in her blood work results, is there a relationship among those factors?

Question 2.

1. Bicarbonate is one of the main bufers in the blood. Provide a defnition of a buf er.

2. Give an equation that allows one to calculate the pH of a buf er solution.

3. Te pKa's for carbonic acid and bicarbonate at 37°C are 3.83 and 10.25, respectively.

i. Write the equation for each of these equilibria.

ii. Below is a titration curve for carbonic acid. Indicate key points on the curve, such as equivalence points and bufer regions. At what pH(s) would you expect carbonic acid species to have ef ective bufering capacity? Explain.

iii. Calculate the ratio of bicarbonate to carbonic acid at pH 7.4, using the pKa value(s) in 2c.

iv. What is unusual about these ratios? Would you expect this to be an ef ective bufer system at pH 7.4? Explain.

Attachment:- One Headache After Another-Biochemistry Edition.rar

Reference no: EM133201112

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