Reference no: EM13898902

The forensic use of ABO blood groups and VNTR allele frequencies

Frequencies of ABO and Rh blood types in the United States

	U.S. Caucasian	U.S. Black	U.S. Asian
0	0.45	0.48	0.40
A	0.40	0.27	0.28
B	0.11	0.21	0.24
AB	0.04	0.04	0.08
Rh+	0.85	0.90	0.99
Rh-	0.15	0.10	0.01

a) What is the probability that a B+ blood stain in the US lefta at the scene of a crime randomly matches a person of the following ancestry

Caucasian
Black
Asian

A genetic sytem that is far more variable than the simple blood types consists of atretches of DNA called VNTRs (variable number of tandem repeats). Each of thes VNTR (also known as minisatellites) loci contain many alleles, most of which are very rate.

Binned	VNTR Locus D1S7 Frequencies in Caucasians        Blacks		Binned a Caucasian D2S44	Ilele frequencies in samples at VNTR loci D17S79  D4S139
Allele	(n=605)	(n=372)	(n=802)	(n=563)	(n=460)
1	0.004	0.007	0.005	0.010	0.004
2	0.006	0.009	0.003	0.003	0.010
3	0.009	0.011	0.016	0.007	0.006
4	0.012	0.007	0.024	0.004	0.014
5	0.011	0.016	0.046	0.015	0.033
6	0.014	0.020	0.034	0.223	0.024
7	0.010	0.011	0.123	0.199	0.040
8	0.029	0.035	0.106	0.263	0.047
9	0.021	0.023	0.084	0.200	0.054
10	0.014	0.030	0.049	0.029	0.071
11	0.028	0.030	0.083	0.032	0.108
12	0.031	0.026	0.039	0.010	0.190
13	0.046	0.044	0.041	0.006	0.129
14	0.067	0.069	0.039		0.095
15	0.057	0.065	0.087		0.036
16	0.061	0.073	0.089		0.036
17	0.069	0.054	0.075		0.103
18	0.055	0.051	0.022
19	0.060	0.047	0.018
20	0.063	0.063	0.008
21	0.079	0.062	0.008
22	0.077	0.060
23	0.077	0.074
24	0.032	0.017
25	0.019	0.027
26	0.050	0.071

b) Calculate the probability that an individual picked at random from the Caucasian population has the following genotype (allele 1/allele 2)

5/22 heterozygote at D1S7
6/8 heterozygote at D2S44
5/9 heterozygote at D17S79
12/12 homozygote at D4S139

c) What is the probability that an individual has full multilocus DNA profile in b)?