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1. 1000 molecules are bouncing at 300K between two wells separated by a free energy gap DG = 6·10-21 J. Calculate how many particles on average are in each well.Boltzmann constant k = 1.38 ·10-23 J/K T = 300K2. A clam-shell protein (see figure below) is more stable in its compact folded state by ?G = -50 kJ/mol than in its open state.a) What is the probability of being open for the intact protein? (give equilibrium constant Keq = [open]/[closed]) (T=300K) b) The pair of amino acids that forms a stabilizing hydrogen bond (14 kJ/mole) in the desolvated contact was replaced by alanines with almost no interaction. How many fold the probability of opening will increase in the mutant?
3. Calculate the Bjerrum length for pairs of ions (+2, +1) and (+2, +2) in water (e=80) at 300K.eo = 8.85 · 10-12 CV-1m-1 4. You know that one mole of water weights 18g and its density is 1g/cm3.a. Calculate density of bulk water (molecules/nm3) and surface density at the air-water interface (molecules/nm2) assuming that average intermolecular distances are the same. b. Given that tension at the air-water interface is 72 mN/m (enthalpy of surface formation) and enthalpy of average H-bond is 3.4 kcal/mole, how many H-bonds are dissatisfied at the surface? c. If average number of H-bonds in the bulk is 3.5/molecule, what fraction of bonds is dissatisfied at the surface?
A population is reproductively isolated. Determine which of the following is primarily responsible for the introduction of new alleles at genetic loci into the population?
Animals obtain energy during a sequence of chemical reaction in which sugar (C6H12O6) and oxygen gas (O2) are reactants. This process produces water (H2O) and carbon dioxide (CO2) as waste products. How might you use radioactive isotope to find out w..
North American supply of salmon has not increased. Freeing up these rivers to allow more wild salmon to propagate will increase U.S. exports which are very good for our economy.
Suppose that a population of 1500 Tasmanian Devils is in H/W equilibrium for a gene that determines fang length. The allele for long fangs is dominant to the allele for short ones.
Discuss and explain resting membrane potential and differentiate the concept of changes in polarity vs changes in concentration gradients.
define the correct sequence of events in the synthesis.
Some sensory neurons in our bodies generate action potentials in response to pressure or movement, allowing us to feel things through our sense of touch.
During swimming there is a large increase in end diastolic volume (EDV) of the heart. This leads to an increase in stroke volume. Explain how the increased EDV leads to the increased SV.
Metabolism uses various ways to ensure that 2 opposing pathways do not occur at the equal time. For the following pair of pathways list 2 ways (different cell location, allosteric effector, covalent modification, different intermediate, different ..
A cell biologist cautiously measured the quantity of DNA in grasshopper cells growing in cell culture. Cells examined throughout the G2 phase of the cell cycle contained 200 units of DNA. What would be the quantity of DNA at G1 of the cell cycle in o..
Discuss these two laws of Thermodynamics and how they relate to the Law of Conservation of Matter. Which of the next may be the path of a protein from the site where its polypeptides are made to its export.
Suppose you infect E. coli cells with two strains of T4 virus. One strain is minute (m), rapid lysis (r) and turbid (t); the other is wild-type for all three markers.
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