Calculate approximately the ability of ibuprofen

Reference no: EM13110732

To calculate approximately the ability of Ibuprofen to move through different tissues in the body(, pharmacologists observed its octanol:water partition ratio, sometimes referred to as "P". )To measure its P, the Ibuprofen added with octanol and H₂O at pH 7.4 and then it was forcefully shaken. The both compounds octanol and H₂O were permitted to separate from each other, and the amount of Ibuprofen in the octanol phase separated by the amount in the H₂O phase was calculated to be P = 11.7. Determine why would the P have been higher or lower if the H₂O had been at pH 5?

Reference no: EM13110732

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