Calculate and interpret the relative risk of disease

Reference no: EM133333209

Questions: Investigators enrolled a total of 1000 subjects into a prospective cohort study examining the role of various genetic and lifestyle factors and their contribution to cardiovascular disease (CVD) risk. Of these 1000 subjects, 200 were found to have a genetic mutation, and the risk of disease among these subjects (the exposed group) was 5%. Among the remaining participants (the unexposed), the risk of disease was 2.5%.

a) Among the exposed, how many subjects developed the disease over the study period, and how many remained disease-free?

b) Among the nonexposed, how many subjects developed the disease over the study period, and how many remained disease-free?

c) Organize this information into a table, using outcomes ('disease', 'no disease', and 'total') as the column headings, and exposure ('exposed', 'non-exposed', and 'total') as the row headings.

d) Calculate and interpret the relative risk of disease associated with this exposure

e) Calculate and interpret the risk difference (attributable risk among the exposed)

f) Calculate and interpret the attributable proportion among the exposed.

g) Calculate the prevalence of the exposure in this cohort

h) Using the full cohort as the total population, calculate and interpret the population attributable risk (PAR) associated with this exposure

i) Using the full cohort as the total population, calculate the proportion of all disease in the total population that is attributable to the exposure

Reference no: EM133333209

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