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Carrying a mutation in one copy of the BRCA1 gene leads to increased risk of developing breast and/or ovarian cancer because as a woman ages, she risks mutating the other copy of the BRCA1 gene. Surprisingly, analysis of some cancers in BRCA1 carriers revealed one mutant copy and one normal copy of BRCA1 at the sequence level. Choose from below the most likely explanation for this observation in the tumors.
a. Cells giving rise to the breast cancer also lost expression of one copy of the p53 gene.
b. The normal BRCA1 copy is methylated, thus is not expressed.
d. The mutant BRCA1 copy is methylated
q1. a 55-year-old male was admitted to the hospital with heart failure. he complains of increasing shortness of breath
Determine what cell type or tissue type would be expected to have a difference in gene expression in someone with hypthyroidism compared to a person without the disorder?
Describe how you would prepare a 0.1 M phosphate buffer with a pH of 7.2. What ratio of conjgate base to acid would you use?
Calculate the number of ATP molecules that can be harvested during complete oxidation of an 18 carbon fatty acid.
Luis had severe amnesia caused by a toxin. This occurred after he consumed shellfish that had been feeding in a red tide. In this situation toxins made by what group of organisms likely caused the illness?
What specific differences would you note compared to the measurements taken today? Explain the differences.
Write a paragraph or two outlining your experience with the problem sets. For example do you now understand the concept behind DNA fingerprinting? Did you find it difficult to determine the father in the paternity suit or the rapist?
q1. what is the purpose of nerve cells?q2. how does their function differ from that of the endocrine system?q3. what
Why people who inherit one mutated allele of the BRCA1 gene have a higher likelihood of developing cancer.
French Canadians have had a difficult time assimlating into Canadian culture and as part of the national identity. What are some of the issues relating to assimilation for Francophones in Canada?
You are interested in examining the metabolism of a new drug that has been developed in your company. How you would determine whether cytochrome P450 is involved in metabolizing the drug, and if so, which subtype is involved.
A homozygous red eyed female Drosophila mates with a red-eyed male Drosophila. Determine what proportion of the female offspring will have white eyes?
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