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Brain cells reacted differently to purines

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A geneticist named Robert Naviaux injected pregnant mice with genes from a virus. As a result, the offsprings' brain cells reacted differently to purines, which are naturally occurring chemicals in the body. When exposed to purines, the cells-including brain cells-would activate a "stress response" that made it harder for them to communicate with one another. These chronically stressed mice exhibited symptoms that are similar to those exhibited by autistic humans, such as avoiding strangers and novel situations. Thus, autism in humans might be caused by a hyperactive stress response by brain cells.

Reference no: EM133286207

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