BI3352 Cancer: Molecular mechanisms, diagnostics

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Reference no: EM132668220

BI3352 Cancer: Molecular mechanisms, diagnostics and therapeutics - Cardiff University

Proforma overview:

These questions are designed to guide the reading of your research paper ahead of SGT1 andto help you extract key points from the paper. Please prepare answers to each question before the tutorial. Your answers will contribute to the group discussion in SGT1. We do not expect you to write detailed (essay style) answers; bullet points will suffice.

Q1: What is the hypothesis being tested and what background work led to this hypothesis?

Q2: Why is this research important? Is there a gap in our knowledge that it sets out to address? How timely is this research; e.g., is this a rapidly expanding research field?

Q3: What model system(s) have the authors used to address their aims? Have multiple systems been used; e.g., in vitro versus in vivo. If so, what impact does this have on the main findings; e.g., is there complementarity between systems that implies generality of the data across species?

Q4: How appropriate is the experimental design? E.g., use of appropriate controls; robust statistical power.Are experiments designed to describe a phenomenon and/or to test a specific molecular function? Have the correct experiments been done to address the aims?

Q5: What figure/part of a figure is the most important element of the story? E.g., directly proves/disproves the hypothesis.

Q6: How do the main findings of the paper impact upon the field? E.g., provide a step-change or incremental advance in our knowledge/understanding. Are the conclusions justified based on the data?

Q7: Have the authors discussed how this research could be developed in future studies? Are there unanswered questions arising from this research that warrant future work? If so, what technologies could be used to address future work?

Q8: In your opinion, is this paper making an important contribution to the field and do you think this research is justified to receive public funding?

Attachment:- diagnostics and therapeutics.rar

Reference no: EM132668220

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